立足临床价值的中药质量化学—生物评价关键技术研究,国家重点研发计划项目,300万元,2023年11月至2026年10月;
2. 国家级青年人才,180万元,2022年12月至2025年11月;
3. 珍稀濒危中药资源新来源的四种开发模式研究,国家重点研发计划任务,70万元,2018年12月至2022年12月;
4. 基于附子药对煎煮机理揭示复方中药质量标志物的研究,国家自然科学基金, 56万元,2021年1月至2024年12月;
5. 基于大鼠心脏毒性指数的生附子毒性预测与皂化煮制减毒机制研究,国家自然科学基金, 17万元,2017年1月至2019年12月;
6. 天商学者科研启动,天津商业大学,200万元,2024年4月至2025年12月。。
代表性学术论文
1. Zi-Dong Qiu, Jin-Long Chen, Wen Zeng, Ying Ma, Tong Chen, Jin-Fu Tang, Chang-Jiang-Sheng Lai*(通讯作者), Lu-Qi Huang*. Real-time toxicity prediction of Aconitum stewing system using extractive electrospray ionization mass spectrometry. Acta Pharm Sin B, 2020, 10(5): 903-912.
2. Zi-Dong Qiu, Xu-Ya Wei, Rui-Qi Sun, Jin-Long Chen, Ting Tan, Jia-Quan Xu, Guang-Hong Cui, Tong Chen, Juan Guo, Chang-Jiang Sheng Lai*(通讯作者), Lu-Qi Huang*.Limitation standard of toxic aconitines in Aconitum proprietary Chinese medicines using on-line extraction electrospray ionization mass spectrometry. Acta Pharm Sin B, 2020, 10: 1511-1520.
3. Xijun Lian*, Ruomeng Zhang, Yujia Shen, Xue-Xiao Cao, Qiuping Wei, Chang-Jiang-Sheng Lai*(通讯作者). Identification of lotus seeds stored over different periods by analyzing the changes in the chemical structure of starch. Journal of Pharmaceutical Analysis, 2026, DOI: 10.1016/j.jpha.2026.101594.
Yanqing Zhang*, Xiaotong Zhao , Li Gong, Changjiangsheng Lai*, Jing Liu, Junbo Xie*. Neuroprotective effects of Gastrodia elata and its compounds in a Caenorhabditis elegans Alzheimer’s disease model. Phytomedicine, 2025, 143: 156876.
6. Wei Li , Yajie Zhang, Xiaoxiao Wang, Yanqing Zhang*, Chang-jiang-sheng Lai*(通讯作者), Junbo Xie*. Melanoidins from stir-frying Atractylodes Macrocephala: Structural characterization, molecular weight distribution, and polyphenol delivery mechanism. Food Chemistry, 2025, 483: 144238.
7. Qing Wang*, Chun-Yu Zhang, Shao-Feng Tang, Chang-Jiang-Sheng Lai*(通讯作者). Natural adsorbents for sample pretreatment: Mechanism insights, greenness assessment and practical applications. Journal of Environmental Chemical Engineering, 2025, 13: 119268.
8. Chongyang Wang, Yourun Chen, Kaiwen Zhang, Yun Huang, Meng Zhao, Qing Wang, Yanqing Zhang, Chang-jiang-sheng Lai*(通讯作者). Decoding the chemical material basis for detoxification and efficacy enhancement of aconite in Zhenwu Decoction using ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry and the Euclidean distance method. Microchemical Journal, 2025, 213: 113569.
9. Ze-Yan Chen, Xu-Ya Wei, Ting Tan, Yu-Lin Feng, Juan Guo, Guang-Hong Cui, Chang-Jiang-Sheng Lai*(通讯作者), Lu-Qi Huang*. Development of a novel unified quality control strategy for proprietary Chinese medicines. Arab J Chem, 2022, 15: 103827.
10. Zi-Dong Qiu, Xiaoping Zhang, Xu-Ya Wei, Konstantin Chingin, Jia-Quan Xu, Wei Gao, Bin Yang, Shuang-Long Wang, Ting Tan, E- Hu Liu, Hai-Yu Xu, Guang-Hong Cui, Juan Guo, Ya-Nan Wang, Ye Shen, Yu-Jun Zhao, Huan-Wen Chen*, Chang-Jiang-Sheng Lai*(通讯作者), Lu-Qi Huang*. Online discovery of the molecular mechanism for directionally detoxification of Fuzi using real-time extractive electrospray ionization mass spectrometry. J Ethnopharmacol, 2021, 277: 114216.
代表性专利
1. 赖长江生,陈焕文,黄璐琦,邱子栋.一种对复杂反应体系中化学成分实时在线监测分析的方法及其专用装置,ZL201810062504.4.
2. 余意,胡明华,尹西拳,赖长江生,肖俊勇.一种栽培品产地识别方法、装置、设备及介质,ZL201911222973.9.
3. 赖长江生,陈焕文,黄璐琦,邱子栋。一种鉴定天麻产品的原料为新鲜天麻或干燥天麻的方法,ZL201611163614.7.
4. 李萍,刘鄂湖,谭婷,赖长江生,曾素玲,一种绝对定量油中甘油酯类成分的方法,ZL201310628545.2.
获奖