一、基本信息

孟丹，女，讲师，硕士生导师，生物技术与食品科学学院， 生物工程系

联系方式：mengd@tjcu.edu.cn

教育背景：

2011.09～2016.06 清华大学 生命科学学院 生物学 理学博士（导师：潘俊敏）

2007.09～2011.07 吉林大学 生命科学学院 药物制剂 理学学士

二、研究方向

从事纤毛组装和解聚的机制研究以及天然产物的功能开发与机制研究。

三、代表性论著

(1) Wang, M.#, Meng, D.#, Zhang, P., Wang, X., Du, G., Brennan, C., Li, S.*, Ho, C.T., Zhao, H.* (2018). Antioxidant Protection of Nobiletin, 5-Demethylnobiletin, Tangeretin, and 5-Demethyl- tangeretin from Citrus Peel in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry 66, 3155-3160.
(2) Meng, D.#, Zhang, P.#, Li, S.*., Ho, C.T., Zhao, H.*(2017). Antioxidant activity evaluation of dietary phytochemicals using Saccharomyces cerevisiae as a model. Journal of Functional Foods 38, 36-44.
(3) Meng, D.#, Zhang, P.#, Zhang, L., Wang, H., Ho, C.T., Li, S.*., Shahidi, F., Zhao,H.*(2017). Detection of cellular redox reactions and antioxidant activity assays. Journal of Functional Foods 37,467-479.
(4) Meng, D. #, and Pan, J.* (2016). A NIMA-related kinase, CNK4, regulates ciliary stability and length. Molecular Biology of the Cell 27, 838-847.
(5) Meng, D.#, Cao, M.#, Oda, T., and Pan, J.* (2014). The conserved ciliary protein Bug22 controls planar beating of Chlamydomonas flagella. Journal of Cell Science 127, 281-287.
(6) Wang, L. #, Gu, L., Meng, D., Wu, Q., Deng, H., and Pan, J.* (2017). Comparative Proteomics Reveals Timely Transport into Cilia of Regulators or Effectors as a Mechanism Underlying Ciliary Disassembly. Journal of proteome research 16, 2410-2418.
(7) Liang, Y. #, Meng, D., Zhu, B., and Pan, J.* (2016). Mechanism of ciliary disassembly. Cellular and Molecular Life Sciences 73, 1787-1802.
(8) Hu, Z. #, Liang, Y., Meng, D., Wang, L., and Pan, J.* (2015). Microtubule-depolymerizing kinesins in the regulation of assembly, disassembly, and length of cilia and flagella. International Review of Cell and Molecular Biology 317,
241-265.
(9) Yang, Y. #, Ran, J. #, Liu, M., Li, D., Li, Y., Shi, X., Meng, D., Pan, J., Ou, G., Aneja, R., Sun, S., Zhou, J. * (2014). CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. Cell research 24, 1342-1353.
(10) Cao, M. #, Meng, D., Wang, L., Bei, S., Snell, W.J.*, and Pan, J.* (2013). Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length. Proceedings of the National Academy of Sciences of the United States of America 110, 12337-12342.

四、科研成果

（1）河北省重点研发计划项目，21327105D，基于近红外线光谱的板栗内腐检测关键技术研究与示范，2021.06-2023.06，第一参与人，在研。

（2） 国家自然科学基金青年项目，31701172，NIMA 相关蛋白激酶 CNK4 调控纤毛稳定性和长度的分子机制研究，2018.01-2020.12，主持，已结题。

（3）天津市自然科学基金青年项目，18JCQNJC09900， Bug22 调控纤毛摆动和组装的分子机制研究，2018.04-2021.03，主持，已结题。
（4）天津商业大学新进人员科研启动项目， R160124， 使用衣藻进行纤毛研究及天然活性物质功能的筛选，2016.10-2019.12，主持，已结题。